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基于LSC-CRC译码的分段极化码编译码方法及系统

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成果归属企业: 深圳大学

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成果介绍

本发明公开了一种热休克转录因子1在调控15kDa硒蛋白表达中的应用。本发明所提供的应用具体为热休克转录因子1在如下任一中的应用：(a1)在靶细胞中促进Sep15蛋白的表达；(a2)在靶细胞中促进Sep15基因的转录；(a3)在靶细胞中增强Sep15启动子的活性。本发明发现了转录因子HSF1能够与Sep15启动子结合，调节Sep15基因转录，促进Sep15蛋白表达。在热激及生理状态发烧的情况下，转录因子HSF1能够启动Sep15转录，提高Sep15表达，从而参与这种生理过程，帮助蛋白正确折叠或帮助蛋白解折叠递送到其他蛋白帮助其正确折叠。在内质网应激下，HSF1也能够促进Sep15表达，从而来参与到内质网蛋白质量控制中，进而促进细胞存活。本发明对于预防和/或治疗内质网应激相关疾病具有重要意义。

成果应用案例介绍

疾病>其它疾病>内质网应激相关疾病

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基本文件流程错误 SQL 调试

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[ BEHAVIOR ] Run Closure @app_init [ RunTime:0.000013s ]
[ CACHE ] INIT File
[ BEHAVIOR ] Run \addons\briefurl\Briefurl @app_init [ RunTime:0.001337s ]
[ BEHAVIOR ] Run \addons\fastflow\Fastflow @app_init [ RunTime:0.000024s ]
[ BEHAVIOR ] Run \addons\notice\Notice @app_init [ RunTime:0.000247s ]
[ BEHAVIOR ] Run \addons\qrcode\Qrcode @app_init [ RunTime:0.000178s ]
[ BEHAVIOR ] Run \addons\treaty\Treaty @app_init [ RunTime:0.000028s ]
[ BEHAVIOR ] Run \addons\upyun\Upyun @app_init [ RunTime:0.000015s ]
[ BEHAVIOR ] Run Closure @app_init [ RunTime:0.000029s ]
[ BEHAVIOR ] Run app\common\behavior\Common @app_init [ RunTime:0.000239s ]
[ LANG ] /www/wwwroot/open.juabc.com/thinkphp/lang/zh-cn.php
[ BEHAVIOR ] Run app\common\behavior\Common @app_dispatch [ RunTime:0.000012s ]
[ ROUTE ] array ( 'type' => 'module', 'module' => array ( 0 => 'index', 1 => 'results', 2 => 'views', ), )
[ HEADER ] array ( 'connection' => 'keep-alive', 'cache-control' => 'max-age=0', 'x-forwarded-for' => '10.1.158.27', 'via' => '1.1 squid-proxy-5b96dc6d46-mbwk5 (squid/6.13)', 'host' => 'www.zqqyzhfw.com', 'accept-encoding' => 'gzip, br, zstd, deflate', 'user-agent' => 'Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)', 'accept' => '*/*', 'content-type' => '', 'content-length' => '', )
[ PARAM ] array ( 'ids' => '4984', )
[ LANG ] /www/wwwroot/open.juabc.com/public/../application/index/lang/zh-cn.php
[ BEHAVIOR ] Run app\common\behavior\Common @module_init [ RunTime:0.000671s ]
[ BEHAVIOR ] Run \addons\upyun\Upyun @module_init [ RunTime:0.000112s ]
[ BEHAVIOR ] Run \addons\wxfollowlogin\Wxfollowlogin @module_init [ RunTime:0.000024s ]
[ BEHAVIOR ] Run \addons\upyun\Upyun @upload_config_init [ RunTime:0.000396s ]
[ BEHAVIOR ] Run \addons\editpage\Editpage @config_init [ RunTime:0.000031s ]
[ BEHAVIOR ] Run \addons\notice\Notice @config_init [ RunTime:0.000022s ]
[ DB ] INIT mysql
[ BEHAVIOR ] Run \addons\csmtable\Csmtable @action_begin [ RunTime:0.000050s ]
[ RUN ] app\index\controller\Results->views[ /www/wwwroot/open.juabc.com/application/index/controller/Results.php ]
[ VIEW ] /www/wwwroot/open.juabc.com/public/../application/index/view/results/views.html [ array ( 0 => 'user', 1 => 'site', 2 => 'config', 3 => 'data', 4 => 'active', 5 => 'login', 6 => 'catelist', 7 => 'views', ) ]
[ BEHAVIOR ] Run \addons\wxfollowlogin\Wxfollowlogin @view_filter [ RunTime:0.000049s ]

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