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一种水泥基材料碳化深度测试方法

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成果归属企业: 深圳大学

成果鉴定时间:

成果介绍

表达分泌金葡菌肠毒素蛋白的重组BCG活菌菌株、活菌疫苗及其构建方法和应用，本发明涉及生物技术领域，特别涉及基因工程技术领域。本发明的目的在于提供一种新型的能够用于预防和治疗人类肿瘤疾病的活菌疫苗。本发明首先提供了一种重组BCG活菌菌株，是将编码野生型金葡菌肠毒素蛋白的野生型金葡菌肠毒素基因序列或者编码突变型金葡菌肠毒素蛋白的突变型金葡菌肠毒素基因序列导入BCG活菌菌株后得到的重组菌株；本发明还提供了该重组菌株的构建方法以及由其得到的活菌疫苗。该活菌菌株能够在细胞中表达分泌出金葡菌肠毒素蛋白，动物学实验证明，将其作为疫苗接种机体后，可以起到预防和治疗癌症的作用。

成果应用案例介绍

医药医疗>疫苗>疫苗; 方法过程>制备方法>制备; 生物(体)>其它微生物>卡介苗(bcg)菌株; 生物(体)>杆菌>重组体芽孢杆菌; 疾病>其它疾病>人类肿瘤疾病

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[ CACHE ] INIT File
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